Io in Humanitas

Unità
Gastroenterologia ed Endoscopia digestiva
Ruolo in ospedale
Medico specialista in Gastroenterologia
Aree mediche di interesse
Malattie Infiammatorie Croniche Intestinali, Gastroenterologia, Endoscopia Digestiva, Medicina Interna.
Consulente Gastroenterologo

Esperienze precedenti

Ultima esperienza lavorativa
Dal 2000 al 2023
Università di Catania, Azienda Ospedaliero-Universitaria Policlinico “G. Rodolico-San Marco” di Catania
Docente di Gastroenterologia (corso di Laurea Magistrale in Medicina e Chirurgia, Scuola di Specializzazione in Malattie dell’Apparato Digerente)
Dirigente medico di I livello UO Medicina Interna
Responsabile Centro Hub della Rete per la terapia delle Malattie Infiammatorie Intestinali della Regione Sicilia

Penultima esperienza lavorativa
Dal 1988 al 2000
Università di Catania, Azienda Garibaldi
Docente di Gastroenterologia (corso di Laurea Magistrale in Medicina e Chirurgia, Scuola di Specializzazione in Malattie dell’Apparato Digerente)
Dirigente medico di I livello UO Patologia Medica/Medicina Interna

Ruolo accademico
Dal 1988 al 1990:
Università di Catania
Tecnico Laureato per la Cattedra di Gastroenterologia

Dal 1990 al 2006:
Università di Catania
Ricercatore Confermato di Gastroenterologia

Dal 2006 al 2023:
Università di Catania
Professore Aggregato di Gastroenterologia

Formazione

Laurea
Laurea in Medicina e Chirurgia
Anno di laurea: 1983
Università degli Studi di Catania

Prima specializzazione
Gastroenterologia ed Endoscopia Digestiva
Anno: 1988
Università degli Studi di Catania

Pubblicazioni ed attività scientifica

1. Gastrointestinal complications after kidney transplantation.
Gioco R, Corona D, Ekser B, Puzzo L, Inserra G, Pinto F, Schipa C, Privitera F, Veroux P, Veroux M.
World J Gastroenterol. 2020 Oct 14;26(38):5797-5811. doi: 10.3748/wjg.v26.i38.5797. PMID: 33132635 Free PMC article. Review.

2. Arterial structure and function in inflammatory bowel disease. Zanoli L, Rastelli S, Inserra G, Castellino P.
World J Gastroenterol. 2015 Oct 28;21(40):11304-11. doi: 10.3748/wjg.v21.i40.11304. PMID: 26523102 Free PMC article. Review.

3. Use of biosimilars in inflammatory bowel disease: a position update of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD).
Fiorino G, Caprioli F, Daperno M, Mocciaro F, Principi M, Viscido A, Fantini MC, Orlando A, Papi C, Annese V, Danese S, Vecchi M, Rizzello F, Armuzzi A; National patients’ association representatives.
Dig Liver Dis. 2019 May;51(5):632-639. doi: 10.1016/j.dld.2019.02.004. Epub 2019 Feb 19.
PMID: 30872085 Review.

4. Inflammation and Aortic Stiffness: An Individual Participant Data Meta-Analysis in Patients With Inflammatory Bowel Disease.
Zanoli L, Boutouyrie P, Fatuzzo P, Granata A, Lentini P, Oztürk K, Cappello M, Theocharidou E, Tuttolomondo A, Pinto A, Cammà C, Licata A, Blanco J, Rastelli S, Inserra G, Castellino P, Laurent S.
J Am Heart Assoc. 2017 Oct 10;6(10):e007003. doi: 10.1161/JAHA.117.007003.
PMID: 29018026 Free PMC article. Review.

5. Increased cardiovascular risk in subjects with a low prevalence of classic cardiovascular risk factors: The inflammatory bowel disease paradox.
Zanoli L, Inserra G, Castellino P.
Trends Cardiovasc Med. 2015 Nov;25(8):705-6. doi: 10.1016/j.tcm.2015.04.001. Epub 2015 Apr 10.
PMID: 25952369 No abstract available.

6. Aortic Stiffness in Patients With Inflammatory Bowel Disease Reduced After Anti-Tumor Necrosis Factor Therapy.
Zanoli L, Inserra G, Cappello M, Ozturk K, Castellino P.
J Am Coll Cardiol. 2019 Mar 5;73(8):981-982. doi: 10.1016/j.jacc.2018.12.032. PMID: 30819367 No abstract available.

7. Subclinical Atherosclerosis in Patients With Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis.
Zanoli L, Signorelli SS, Inserra G, Castellino P.
Angiology. 2017 May;68(5):463. doi: 10.1177/0003319716675076. Epub 2016 Oct 26.
PMID: 27784730 No abstract available.

8. Anxiety, depression, chronic inflammation and aortic stiffness in Crohn’s disease: the brain– gut–vascular axis.
Zanoli L, Tuttolomondo A, Inserra G, Cappello M, Granata A, Malatino L, Castellino P; Inflammation Arterial Stiffness Study Group.
J Hypertens. 2020 Oct;38(10):2008-2017. doi: 10.1097/HJH.0000000000002517. PMID: 32890277

9. Pulse wave velocity differs between ulcerative colitis and chronic kidney disease.
Zanoli L, Lentini P, Boutouyrie P, Fatuzzo P, Granata A, Corrao S, Gaudio A, Inserra G, Rapisarda F, Rastelli S, Laurent S, Malatino LS, Castellino P.
Eur J Intern Med. 2018 Jan;47:36-42. doi: 10.1016/j.ejim.2017.08.020. Epub 2017 Aug 19. PMID: 28830726

10. Real-Life Effectiveness and Safety of Golimumab and Its Predictors of Response in Patients with Ulcerative Colitis.
Bossa F, Biscaglia G, Valvano MR, Costantino G, Lauria A, Clemente R, Ferracane C, Shahini E, Mendolaro M, Grossi L, Mazzuoli S, Rispo A, Pranzo G, Sebkova L, Tursi A, Miranda A, Patturelli M, Spagnuolo R, Ricciardelli C, Sgarro C, Paese P, Inserra G, Azzarone A, Nardone O, Fries W, Buccianti N, Privitera AC, Principi MB, Cappello M, Guglielmi FW, Romano M, Riegler G, Fanigliulo L, Melina R, Andriulli A.
Dig Dis Sci. 2020 Jun;65(6):1767-1776. doi: 10.1007/s10620-019-05904-z. Epub 2019 Nov 13. PMID: 31722059

11. Arterial stiffness in inflammatory bowel disease: a systematic review and meta-analysis. Zanoli L, Rastelli S, Granata A, Inserra G, Empana JP, Boutouyrie P, Laurent S, Castellino P. J Hypertens. 2016 May;34(5):822-9. doi: 10.1097/HJH.0000000000000867.
PMID: 26882040

12. Disease patterns in late-onset ulcerative colitis: Results from the IG-IBD “AGED study”.
Fries W, Viola A, Manetti N, Frankovic I, Pugliese D, Monterubbianesi R, Scalisi G, Aratari A, Cantoro L, Cappello M, Samperi L, Saibeni S, Casella G, Mocci G, Rea M, Furfaro F, Contaldo A, Magarotto A, Calella F, Manguso F, Inserra G, Privitera AC, Principi M, Castiglione F, Caprioli F, Ardizzone S, Danese S, Papi C, Bossa F, Kohn A, Armuzzi A, D’Incà R, Annese V, Alibrandi A, Bonovas S, Fiorino G; Italian Group for the study of Inflammatory Bowel Disease (IG-IBD).
Dig Liver Dis. 2017 Jan;49(1):17-23. doi: 10.1016/j.dld.2016.09.006. Epub 2016 Sep 21. PMID: 27717794

13. Can Conventional and Diffusion-Weighted MR Enterography Biomarkers Differentiate Inflammatory from Fibrotic Strictures in Crohn’s Disease?
Foti PV, Travali M, Farina R, Palmucci S, Coronella M, Spatola C, Puzzo L, Garro R, Inserra G, Riguccio G, Zanoli L, Basile A.
Medicina (Kaunas). 2021 Mar 15;57(3):265. doi: 10.3390/medicina57030265. PMID: 33803953 Free PMC article.

14. Arterial stiffness is increased in patients with inflammatory bowel disease.
Zanoli L, Cannavò M, Rastelli S, Di Pino L, Monte I, Di Gangi M, Boutouyrie P, Inserra G, Laurent S, Castellino P.
J Hypertens. 2012 Sep;30(9):1775-81. doi: 10.1097/HJH.0b013e3283568abd. PMID: 22796713

15. Responsibility of hepatitis C virus in the development of hepatocellular carcinoma: From molecular alterations to possible solutions.
Bertino G, Malaguarnera G, Frazzetto E, Sciuto A, Inserra G, Zanghì GN, Malaguarnera M. World J Hepatol. 2018 Jun 27;10(6):448-451. doi: 10.4254/wjh.v10.i6.448.
PMID: 29988862 Free PMC article.

16. Inflammation and Aortic Pulse Wave Velocity: A Multicenter Longitudinal Study in Patients With Inflammatory Bowel Disease.
Zanoli L, Ozturk K, Cappello M, Inserra G, Geraci G, Tuttolomondo A, Torres D, Pinto A, Duminuco A, Riguccio G, Aykan MB, Mulé G, Cottone S, Perna AF, Laurent S, Fatuzzo P, Castellino P, Boutouyrie P.
J Am Heart Assoc. 2019 Feb 5;8(3):e010942. doi: 10.1161/JAHA.118.010942.
PMID: 30712441 Free PMC article.

17. Persistence on Anti-Tumour Necrosis Factor Therapy in Older Patients with Inflammatory Bowel Disease Compared with Younger Patients: Data from the Sicilian Network for Inflammatory Bowel Diseases (SN-IBD).
Porcari S, Viola A, Orlando A, Privitera AC, Ferracane C, Cappello M, Vitello A, Siringo S, Inserra G, Magnano A, Mocciaro F, Di Mitri R, Belluardo N, Fidanza O, Garufi S, Magrì G, Bertolami C, Carroccio A, Macaluso FS, Renna S, Ventimiglia M, Alibrandi A, Cottone M, Fries W; Sicilian Network for Inflammatory Bowel Diseases (SN-IBD).
Drugs Aging. 2020 May;37(5):383-392. doi: 10.1007/s40266-020-00744-3. PMID: 32016824

18. A real life comparison of the effectiveness of adalimumab and golimumab in moderate-to- severe ulcerative colitis, supported by propensity score analysis.
Renna S, Mocciaro F, Ventimiglia M, Orlando R, Macaluso FS, Cappello M, Fries W, Mendolaro M, Privitera AC, Ferracane C, Pisana V, Magnano A, Pluchino D, Inserra G, Scarpulla G, Garufi S, Carroccio A, Siringo S, Di Mitri R, Cottone M, Orlando A.
Dig Liver Dis. 2018 Dec;50(12):1292-1298. doi: 10.1016/j.dld.2018.06.008. Epub 2018 Jun 22. PMID: 30007516

19. Increased arterial stiffness in inflammatory bowel diseases is dependent upon inflammation and reduced by immunomodulatory drugs.
Zanoli L, Rastelli S, Inserra G, Lentini P, Valvo E, Calcagno E, Boutouyrie P, Laurent S, Castellino P.
Atherosclerosis. 2014 Jun;234(2):346-51. doi: 10.1016/j.atherosclerosis.2014.03.023. Epub 2014 Mar 30.
PMID: 24732573

20. Crohn’s disease of the small bowel: evaluation of ileal inflammation by diffusion-weighted MR imaging and correlation with the Harvey-Bradshaw index.
Foti PV, Farina R, Coronella M, Palmucci S, Ognibene N, Milone P, Conti Bellocchi C, Samperi L, Inserra G, Laghi A, Ettorre GC.
Radiol Med. 2015 Jul;120(7):585-94. doi: 10.1007/s11547-015-0502-8. Epub 2015 Feb 4. PMID: 25650083

21. A Propensity Score-matched Comparison of Infliximab and Adalimumab in Tumour Necrosis Factor-α Inhibitor-naïve and Non-naïve Patients With Crohn’s Disease: Real-Life Data From the Sicilian Network for Inflammatory Bowel Disease.
Macaluso FS, Fries W, Privitera AC, Cappello M, Siringo S, Inserra G, Magnano A, Di Mitri R, Mocciaro F, Belluardo N, Scarpulla G, Magrì G, Trovatello A, Carroccio A, Genova S, Bertolami C, Vassallo R, Romano C, Citrano M, Accomando S, Ventimiglia M, Renna S, Orlando R, Rizzuto G, Porcari S, Ferracane C, Cottone M, Orlando A; Sicilian Network for Inflammatory Bowel Diseases [SN-IBD].
J Crohns Colitis. 2019 Feb 1;13(2):209-217. doi: 10.1093/ecco-jcc/jjy156. PMID: 30295785

22. Late-onset Crohn’s disease: a comparison of disease behaviour and therapy with younger adult patients: the Italian Group for the Study of Inflammatory Bowel Disease ‘AGED’ study.
Viola A, Monterubbianesi R, Scalisi G, Furfaro F, Rea M, Saibeni S, Aratari A, Bringiotti R, Casella G, Cantoro L, Frankovic I, Calella F, Pugliese D, Orlando S, Samperi L, Cappello M, Mocci G, Manetti N, Annese V, Privitera AC, Inserra G, Caprioli F, D’Incà R, Principi M, Papi C, Castiglione F, Danese S, Ardizzone S, Bossa F, Kohn A, Manguso F, Alibrandi A, Fiorino G, Armuzzi A, Fries W; Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD). Eur J Gastroenterol Hepatol. 2019 Nov;31(11):1361-1369. doi: 10.1097/MEG.0000000000001546.
PMID: 31567640

23. Patient and physician views on the quality of care for inflammatory bowel disease after one- year follow-up: Results from SOLUTION-2, a prospective IG-IBD study.
Daperno M, Bortoli A, Kohn A, Politi P, Marconi S, Ardizzone S, Cortelezzi CC, Grasso G, Ferraris L, Milla M, Spina L, Guidi L, Losco A, Inserra G, Sablich R, Morganti D, Bodini G, Comberlato M; Italian Group for the study of Inflammatory Bowel Disease IG-IBD.
Dig Liver Dis. 2017 Sep;49(9):997-1002. doi: 10.1016/j.dld.2017.05.008. Epub 2017 May 18. PMID: 28595949

24. Letter: SPOSIB SB2-a Sicilian prospective observational study of IBD patients treated with infliximab biosimilar SB2.
Macaluso FS, Cappello M, Giuffrida E, Fries W, Centritto A, Privitera AC, Inserra G, Vassallo R, Magnano A, Vinci E, Garufi S, Ventimiglia M, Renna S, Orlando R, Rizzuto G, Cottone M, Orlando A; Sicilian Network for Inflammatory Bowel Disease (SN-IBD).
Aliment Pharmacol Ther. 2019 Jan;49(2):234-236. doi: 10.1111/apt.15071. PMID: 30589969 No abstract available.

25. Patient and physician views on the quality of care in inflammatory bowel disease: results from SOLUTION-1, a prospective IG-IBD study.
Bortoli A, Daperno M, Kohn A, Politi P, Marconi S, Monterubbianesi R, Castiglione F, Corbellini A, Merli M, Casella G, D’Incà R, Orlando A, Bossa F, Doldo P, Lecis P, Valpiani D, Danese S, Comberlato M; Italian Group for the study of Inflammatory Bowel Disease (IG- IBD).
J Crohns Colitis. 2014 Dec;8(12):1642-52. doi: 10.1016/j.crohns.2014.07.004. Epub 2014 Aug 10.
PMID: 25113898

26. Omeprazole vs. ranitidine in short-term treatment of Helicobacter pylori positive duodenal ulcer patients.
Catalano F, Mangiameli A, Inserra G, Monello S, Brogna A, Sofia M, Rizzo G, Ayoubi Khajekini M, Blasi A.
Ital J Gastroenterol. 1991 Jan;23(1):9-11. PMID: 1747501 Clinical Trial.

Ha partecipato con relazioni, presentazioni e abstract a numerosi congressi e corsi nazionali e internazionali